IMB-808

Code: SML1945-5MG D2-231

Biochem/physiol Actions

IMB-808 is a potent Liver X receptor α and β (LXRα/β) partial dual agonist that promotes expression of genes related to reverse ch...


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€83.75 5MG
€103.01 inc. VAT

Biochem/physiol Actions

IMB-808 is a potent Liver X receptor α and β (LXRα/β) partial dual agonist that promotes expression of genes related to reverse cholesterol transport (including ABCA1 and ABCG1), and associated with cholesterol metabolism pathway in multiple cell lines (including ApoE). Also IMB-808 promotes cholesterol efflux from macrophages and reduced the accumulated lipids of foam cells.

assay≥98% (HPLC)
colorwhite to beige
formpowder
SMILES stringFC1=C(NC(CN(C)C(C2=CC(OCCO3)=C3C=C2)=O)=O)C=CC(F)=C1F
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
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