Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

General description

A nonpolar, uncharged amino acid.

A non-essential, optically inactive, non-chiral amino acid. It is the smallest of the 20 natural amino acids. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Shapiro, S. 1997. Neurosurgery 40, 168.Mount, H., et al. 1991. Mol. Pharmacol.39, 205.Thompson, A.M., et al. 1989. Nature338, 422.

Packaging

500 g in Glass bottle

1 kg in Glass bottle

Warning

Toxicity: Standard Handling (A)