Furin Substrate; Fluorogenic

Code: 344935-5MG D2-231

Biochem/physiol Actions

kcat/Km ~ 2 x 104 s-1M-1 for furin

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetFluoroge...


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€318.90 EACH
€392.25 inc. VAT

Biochem/physiol Actions

kcat/Km ~ 2 x 104 s-1M-1 for furin

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetFluorogenic substrate for furin

General description

A fluorogenic substrate for furin (kcat/Km ~2 X 104 M-1 s-1), a mammalian homolog of the yeast Kex2 endoprotease. Also serves as a substrate for related protein, prohormone convertase 2 (PC2) (kcat/Km ~6 X 103 M-1 s-1). Excitation max: ~360-380 nm; emission max: ~430-460 nm).

A fluorogenic substrate for furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km ~ 2 x 104 s-1M-1).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Lamango, N.S., et al. 1996. Arch. Biochem. Biophys.330, 238.Hatsuzawa, K., et al. 1992. J. Biol. Chem. 267, 16094.

Packaging

5 mg in Plastic ampoule

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°). Stock solutions are stable for up to 3 months at -20°C.

Sequence

Pyr-Arg-Thr-Lys-Arg-AMC

Warning

Toxicity: Standard Handling (A)

assay≥95% (HPLC)
colorwhite
fluorescenceλex 360 - 380 nm, λem 430-460 nm
formsolid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilitywater: 10 mg/mL, DMSO: soluble
storage conditiondesiccated (hygroscopic), protect from light, OK to freeze
storage temp.−20°C
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