FMOC-TOAC-OH

Code: 8523428100 D2-231

Analysis Note

Color (visual): white to yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testAssay (HPLC, area%): ≥ 98.0 % (a/a)


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€224.70 EACH
€276.38 inc. VAT

Analysis Note

Color (visual): white to yellow to beigeAppearance of substance (visual): powderIdentity (IR): passes testAssay (HPLC, area%): ≥ 98.0 % (a/a)

General description

Fmoc-TOAC-OH is a useful tool for the incorporation of the ESR spin-label TOAC into peptide sequences [1]. Incorporation of this derivative and the following residue is best achieved using HATU activation. TFA/water/TIS should be used for cleavage of TOAC-containing peptides. The use of EDT should be avoided as it can cause permanent reduction of the nitroxide radical [2]. Following cleavage, the TOAC peptide should be treated with aqueous ammonia in air to regenerate the nitroxide from the hydroxylamine that is generated by the TFA treatment.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

application(s)peptide synthesis
assay≥98.0% (HPLC)
formpowder
functional groupFmoc
manufacturer/tradenameNovabiochem®
Quality Level200
reaction suitabilityreaction type: Fmoc solid-phase peptide synthesis
storage temp.2-8°C
Cas Number93372-25-9
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