Analysis Note

Color (visual): white to slight yellow to beigeAppearance of substance (visual): powderIdentity (IR): conformsEnantiomeric purity: ≥ 99.0 % (a/a)Purity (TLC(CMA2)): ≥ 98 %Purity (TLC(157A)): ≥ 98 %Assay (HPLC, area%): ≥ 98.0 % (a/a)Solubility (1 mmole in 2 ml DMF): clearly solubleAssay (acidimetric): ≥ 97.0 %Water (K. F.): ≤ 1.5 %For TLC-Systems see our General Catalog

General description

Orthogonally-protected building block for the synthesis of head-to-tail cyclic peptides [1-5].

The α-allyl ester can be selectively removed in the presence of Fmoc- and tBu-based protecting groups by treatment with Pd(Ph₃P)₄/ CHCl₃/AcOH/NMM [6], thereby facilitating the synthesis of branched esters, amides, lactones and lactams incorporating an aspartyl unit.

The product number for this product was previously 04-12-1157.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: 04-12-1157

Packaging

1 g in Glass bottle