Biochem/physiol Actions

Target IC₅₀: 40 pM against calcineurin (protein phosphatase 2B

Primary Targetcalcineurin

Product does not compete with ATP.

General description

Type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC₅₀ = 40 pM). May also have varied effects on ion channels.

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC₅₀ = 40 pM). May also have varied effects on ion channels.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Richter, A., et al. 1995. Biochem. Pharmacol.49, 367.Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.

Packaging

10 mg in Alu drum

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Toxic (F)