Biochem/physiol Actions
Target IC50: 40 pM against calcineurin (protein phosphatase 2B
Primary Targetcalcineurin
Product does not compete with ATP.
General description
Type II pyrethroid insecticide. Potent inhibitor of calcineurin (protein phosphatase 2B, IC50 = 40 pM). May also have varied effects on ion channels.
Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
Synthetic type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B; IC50 = 40 pM). May also have varied effects on ion channels.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Richter, A., et al. 1995. Biochem. Pharmacol.49, 367.Wang, J.H., and Stelzer, A. 1994. NeuroReport 5, 2377.Enan, E., and Matsumura, F. 1992. Biochem. Pharmacol.43, 1777.Narahasi, T. 1992. Trends Pharmacol. Sci.13, 236.
Packaging
10 mg in Alu drum
Reconstitution
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Warning
Toxicity: Toxic (F)
This product has met the following criteria: