Application

Crotaline has been used in hydrochloric acid (HCl) and injected into experimental animals to induce-pulmonary hypertension.

Biochem/physiol Actions

Crotaline induces pulmonary vascular syndrome in rats. It is considered toxic and results in hepatic cirrhosis, enlarged liver, sinusoidal obstruction syndrome and right ventricular hypertrophy.

General description

Crotaline is a macrocyclic compound belonging to the pyrrolizidine alkaloid family. It is naturally present in Crotalaria spectabilis.

Packaging

1 g in glass bottle

500 mg in glass bottle

form	powder
InChI key	QVCMHGGNRFRMAD-XFGHUUIASA-N
InChI	1S/C16H23NO6/c1-9-13(18)23-11-5-7-17-6-4-10(12(11)17)8-22-14(19)16(3,21)15(9,2)20/h4,9,11-12,20-21H,5-8H2,1-3H3/t9-,11+,12+,15+,16-/m0/s1
mp	204 °C (dec.) (lit.)
SMILES string	[H][C@@]12[C@H]3CCN1CC=C2COC(=O)[C@](C)(O)[C@](C)(O)[C@@H](C)C(=O)O3
storage temp.	2-8°C

Safety Data Sheet for C2401-1G

Cas Number	315-22-0
Hazard Class	6.1
Un Number	1544
Pack Group	III

This product has met the following criteria to qualify for the following awards:

Crotaline,

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