Biochem/physiol Actions
Target IC50: 70 nM against PDE III
Reversible: no
Product does not compete with ATP.
Cell permeable: yes
Primary TargetPDE 3
General description
A cell-permeable selective inhibitor of cGMP-inhibited phosphodiesterase (PDE III; IC50 = 70 nM).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Verghese, M.W., et al. 1995. J. Pharmacol. Exp. Ther. 272, 1313.Christensen, S.B., and Trophy, T.J. 1994. Ann. Rep. Med. Chem. 29, 185.Tang, K.M., et al. 1994. Eur. J. Pharmacol. 268, 105.
Packaging
10 mg in Plastic ampoule
Reconstitution
Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.
Warning
Toxicity: Standard Handling (A)
This product has met the following criteria to qualify for the following awards: