Biochem/physiol Actions

Ceramide synthase (cerS) catalyzes the acylation of sphinganine (dihydrosphingosine) to yield dihydroceramide and sphingosine to yield ceramide. There are six cerS (cerS1-6), which differ in their specificity to yield ceramides of different chain length. Ceramide is a key intermediate in sphingolipid metabolism and an key signaling molecule.

General description

The CerS Assay Kit provides an easy to use assay for measuring CerS activity in biological samples. This Kit offers the advantage of a short assay time requiring only small amounts of biological material while eliminating TLC as a separation technique with its attendant degradation of NBD sphinganine.

Packaging

Kit contains:0.3mg 16:0 fatty acyl-CoA0.1mg NBD Sphinganine

Storage and Stability

Note: this product should be stored at -20° for up to 6 months.