General description

An active constituent of cayenne pepper with excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced responses in rat PC12 cells. Exhibits anti-nociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.

An active constituent of cayenne pepper. Has excitatory and desensitizing effects on a subset of primary afferent sensory neurons. An antagonist of acetylcholine-induced respones in rat pheochromocytoma cells. Exhibits antinociceptive and anti-inflammatory effects. Inhibits NF-κB activation by TNF. Reversibly inhibits platelet aggregation.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

Singh, S., et al. 1996. J. Immunol.157, 4412.Nakazawa, K., et al. 1994. Br. J. Pharmacol.113, 296.Simmons, D.D., et al. 1994. Int. J. Dev. Neurosci.12, 517.Takaki, M., et al. 1994. J. Mol. Cell. Cardiol.26, 1227.Bevan, S., and Szolcsanyi, J. 1990. Trends Pharmacol. Sci.11, 330.Pernow, B., et al. 1985. J. Immunol.135, 8125.

Packaging

100 mg in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Warning

Toxicity: Toxic (F)