BX-912

Code: SML1086-25MG D2-231

Biochem/physiol Actions

BX-912 is a potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1). The IC50 values for direct inhibition of kinase activity or inhi...


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€298.20 25MG
€366.79 inc. VAT
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Biochem/physiol Actions

BX-912 is a potent inhibitor of PDK1 (3-Phosphoinositide dependent protein kinase-1). The IC50 values for direct inhibition of kinase activity or inhibition in a cell based assay are 26 nM and 12 nM, respectively. BX-912 inhibits the growth of PC-3 tumor cells grown on soft agar more potently than cells grown on plastic (IC50 = 320 nM vs. 5.5 mM, respectively).

Packaging

5, 25 mg in glass bottle

assay≥95% (HPLC)
colorwhite to beige
formpowder
Quality Level100
solubilityDMSO: 10 mg/mL, clear
storage conditiondesiccated
storage temp.−20°C
Cas Number702674-56-4
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