BAPTA/AM

Code: 196419-100MG D2-231

General description

Membrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly...


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Your Price
€867.00 100MG
€1,066.41 inc. VAT

General description

Membrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA.Prevents cocaine-induced ventricular fibrillations. Abolishes vitamin D3-induced increase in intracellular Ca2+. Induces inactivation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.

Membrane-permeable form of BAPTA. Can be loaded into a wide variety of cells, where it is hydrolyzed by cytosolic esterases and is trapped intracellularly as the active chelator BAPTA. Prevents cocaine-induced ventricular fibrillations. Induces inactivation of protein kinase C. Also inhibits thapsigargin-induced apoptosis in rat thymocytes.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Bissonnette, M., et al. 1994. Am. J. Physiol.267, G465.Jiang, S., et al. 1994. Exp. Cell Res.212, 84.Billman, G.E. 1993. Am. J. Physiol. 265, H1529.Dieter, P., et al. 1993. Biol. Chem. Hoppe Seyler 374, 171.Harrison, S.M., and Bers, D.M. 1987. Biochim. Biophys. Acta 925, 133.Harrison, S.M., and Bers, D.M. 1987. J. Biophys.51, 102A.Marban, E., et al. 1986. J. Clin. Invest.78, 1185.Tsien, R.Y. 1981. Nature290, 527.Tsien, R.Y. 1980. Biochemistry19, 2396.

Packaging

Packaged under inert gas

25, 100 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot, purge with inert gas and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Warning

Toxicity: Irritant (B)

assay≥90% (TLC)
colorlight yellow
formsolid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inambient
solubilityDMSO: 10 mg/mL
storage conditionprotect from light, OK to freeze
storage temp.−20°C
Cas Number126150-97-8
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