Application
This hRNF20 antibody is validated for use in WB for the detection of the hRNF20 protein.
General description
BRE1-A (E3 ubiquitin-protein ligase BRE1A) also known by it′s gene name hRNF20, plays a role in histone code and gene regulation as a component of the RNF20/40 E3 ubiquitin-protein ligase complex. That complex mediates monoubiquitination of ′Lys-120′ of histone H2B,which is a specific tag for epigenetic transcriptional activation as well as a prerequisite for histone H3 ′Lys-4′ (H3K4me) and ′Lys-79′ (H3K79me) methylation.
Immunogen
GST-tagged recombinant protein corresponding to human hRNF20.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Quality
Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected hRNF20 in 10 µg of A431 cell lysate.
Target description
~113 kDa observed
This product has met the following criteria to qualify for the following awards: