Application

Research CategoryApoptosis & Cancer

Detect TACI using this Anti-TACI Antibody validated for use in western blotting & ICC.

Research Sub CategoryApoptosis - Additional

Immunocytochemistry Analysis: 2 µg/mL from a representative lot detected TACI in K562 cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Members in the TNF superfamily regulate immune responses and induce apoptosis. TACI (also known as Tumor necrosis factor receptor superfamily member 13B, transmembrane activator and CAML interactor, and CD267) binds BAFF and April and its ligands regulate humoral immune responses, activate NF-kB and c-Jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

Immunogen

Epitope: N-terminus

KLH-conjugated synthetic peptide corresponding to the N-terminus of human TACI.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Quality

Evaluated by Western Blotting in K562 and U937 cell lysates.

Western Blotting Analysis: 5 µg/mL of this antibody detected TACI in K562 and U937 cell lysates.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~32 kDa observed. Uncharacterized bands may be observed in some lysate(s).