Application

Rabbit Anti-SP7 antibody is suitable for use in western blot (0.125µg/ml) and immunohistochemical (4-8µg/ml) assays.

Biochem/physiol Actions

SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of bone cell differentiation.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

SP7 is a zinc-finger containing transcription factor that regulates BMP6-induced osteoblast differentiation.Rabbit Anti-SP7 antibody recognizes bovine, human, mouse, and rat SP7.

Immunogen

Synthetic peptide directed towards the C terminal region of human SP7

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: RTHGEPGPGPPPSGPKELGEGRSTGEEEASQTPRPSASPATPEKAPGGSP