Application

Anti-SOX8 antibody produced in rabbit is suitable for western blotting at a concentration of 1 µg/ml.

Biochem/physiol Actions

Sox8 is expressed in Sertoli cells and regulates the spermatogenesis and spermatogenic cycle. Deficiency of Sox8 results in degeneration of adipose tissue and mild osteopenia.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Sox8 belongs to the SoxE family of transcription factors that are critical for development of neural crest cells. The Sox gene family has been implicated in a number of developmental disorders.

Immunogen

Synthetic peptide directed towards the C terminal region of human SOX8

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: ASPTETGPPRPHIKTEQPSPGHYGDQPRGSPDYGSCSGQSSATPAAPAGP