Application

Anti-SLC15A4 antibody produced in rabbit is suitable for western blotting at a concentration of 0.25µg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8µg/ml.

Biochem/physiol Actions

SLC15A4 (PHT1; PTR4) is a peptide/histidine transporter expressed in the brain and the retina. This protein enables plasmacytoid dendritic cells to sense toll-like receptor ligands that aid in triggering immune responses to persistent viral infections. The expression of SLC15A4 has been implicated in the pathogenesis of lupus.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide directed towards the N terminal region of human SLC15A4

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: MEGSGGGAGERAPLLGARRAAAAAAAAGAFAGRRAACGAVLLTELLERAA