Application

Research Sub CategoryNuclear Receptors

Research CategoryEpigenetics & Nuclear Function

This Anti-SKI Antibody is validated for use in Western Blotting for the detection of SKI.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Ski oncogene (SKI) is also called Proto-oncogene c-Ski. Ski acts as a repressor of TGF-beta signaling. Ski is thought to be involved in terminal differentiation of skeletal muscle cells, but not in driving cells toward a myogenic lineage.

Immunogen

KLH-conjugated linear peptide corresponding to human SKI.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blotting in Raji cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SKI in 10 µg of Raji cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~95 kDa observed