Analysis Note
ControlMouse brain tissue lysate
Application
Research Sub CategoryTranscription Factors
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected SATB2 in human brain tissue.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected SATB2 in human brain cells.
Research CategoryEpigenetics & Nuclear Function
Detect Special AT-rich sequence-binding protein 2 using this rabbit polyclonal antibody, Anti-SATB2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Special AT-rich sequence-binding protein 2 (SATB2) contains 2 CUT DNA-binding domains and one homeobox DNA binding domain belonging to the CUT homeobox family. SATB2 binds to DNA at the nuclear matri or scaffold-associated regions. SATB2 is highly expressed in adult brain, moderately expressed in fetal brain, and weakly expressed in adult liver, kidney, and spinal cord. Mutations in SATB2 have been associated with cleft palate.
Immunogen
KLH-conjugated linear peptide corresponding to the N-terminus of human SATB2.
Epitope: N-terminus
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Quality
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 4 µg/mL of this antibody detected SATB2 in 15 µg of mouse brain tissue lysate.
Specificity
This antibody recognizes the N-terminus of SATB2.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Target description
~90 kDa observed
This product has met the following criteria to qualify for the following awards: