Application

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue.

This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35.

General description

RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Quality

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate.

Specificity

This antibody recognizes RAB35 at the C-terminus.

Target description

~19 kDa observed. The calculated molecular weight is 23 kDa