Application

Immunofluorescence Staining:
Independent laboratory demonstrated this antibody worked in Immunofluorescence studies at a 1:100-1:500 dilution.

Immunoprecipitation (IP):
Independent laboratory demonstrated this antibody works in Immunoprecipitation.

Detect Rab13 using this Anti-Rab13 Antibody validated for use in WB, IP & IF.

General description

Rab proteins are members of the Ras superfamily of small G-Proteins. At least 60 isoforms have been identified. These GTPases are primarily involved in vesicle trafficking and it is believed that a different Rab protein may be needed for each step of the vesicular transport. It is thought Rab4 and Rab11 are involved in internalization, sorting, and transport to lysosomes or recycling, of several membrane proteins, including GPCRs, GLUT-4, Aquaporin-2, or the H+/K+ ATPase.

Immunogen

Sythnetic peptide of amno acids 129-148 of rat Rab13

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Affinity Purified rabbit IgG in storage buffer containing tri-citrate-phosphate, pH 7-8 and 0.1% sodium azide.

Quality

Western Blot Analysis:
This lot detected Rab13 at 1:1,000 (1g/mL) dilution in lysates from PC12 lysate resolved via SDS-PAGE and transferred to PVDF (Immobilon-P).

Specificity

Recognizes Rab13

Target description

25 kDa