Application
Rabbit Anti-MXD4 antibody can be used for western blot applications at a concentration of 0.5 µg/ml.
Biochem/physiol Actions
MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
MXD4 is a basic helix-loop-helix (bHLH) transcription factor that regulates the proliferation of blood precursors during the start of hematopoietic development.Rabbit Anti-MXD4 antibody recognizes canine, bovine, human, mouse, and rat MXD4.
Immunogen
Synthetic peptide directed towards the N terminal region of human MXD4
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: SLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNN
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