Analysis Note

ControlEL4 cell lysate

Application

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected LFG in mouse brain tissue.

Research Sub CategoryNeurodegenerative Diseases

Research CategoryNeuroscience

Detect LFG using this rabbit polyclonal antibody, Anti-LFG Antibody validated for use in western blotting & IHC.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Protein lifeguard 2 (LFG) is an antiapoptotic protein belonging to the BI1 family. LFG inhibits the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-death signal. LFG is expressed at high levels in the brain especially in the hippocampus. It is also highly expressed in breast cancer tissues and correlates with the grade of tumor (grade II/grade III) in primary breast tumors.

Immunogen

KLH-conjugated linear peptide corresponding to human LFG.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Quality

Evaluated by Western Blotting in EL4 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected LFG in 15 µg of EL4 cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~35 kDa observed.