Application

Anti-IKBKG antibody produced in rabbit is suitable for western blotting at a concentration of 1.25 µg/ml.

Biochem/physiol Actions

The Inhibitor of nuclear factor-κB (IκB) kinase (IKK) complex is a central regulator of NF-κB signaling and activation of target genes. The IKK complex is made up of IKK1, IKK2 and NEMO or IKK γ. Two subunits of NEMO bind the IKK1-IKK2 heterodimer to make up the IKK complex. IKK γ lacks a catalytic domain but has regulatory function on the IKK complex.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide directed towards the middle region of human IKBKG

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: LGELQESQSRLEAATKECQALEGRARAASEQARQLESEREALQQQHSVQV