Anti-ESRRB

Application

Rabbit Anti-ESRRB antibody can be used for western blot applications at a concentration of 0.5µg/ml.

Biochem/physiol Actions

ESRRB encodes a protein with similarity to the estrogen receptor. Its function is unknown; however, a similar protein in mouse plays an essential role in placental development. Sequence Note: The sequence AF094517.1 is from a chimeric clone. Only the ESRRB sequence was propagated into this RefSeq record.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Estrogen-related-receptor β (Esrrb) is a member of the nuclear orphan receptor family that can induce cell differentiation in cultured mouse embryonic stem (ES) cells. Studies have reported that Esrrb can stimulate Oct4 transcription. This receptor can also regulate the pulripotency of ES cells.Rabbit Anti-ESRRB antibody recognizes human, mouse, rat, bovine, and canine ESRRB.

Immunogen

Synthetic peptide directed towards the N terminal region of human ESRRB

Sequence

Synthetic peptide located within the following region: RHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANG