Analysis Note

ControlHuman spleen tissue

Application

Research CategoryNeuroscience

Research Sub CategoryDevelopmental Signaling

Anti-CD6 Antibody is a highly specific rabbit polyclonal antibody, that targets CD6 & has been tested in IHC.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

T-cell differentiation antigen CD6, also known as CD_antigen CD6, T12, and TP120. CD6 is a monomeric 105- or 130-kD membrane glycoprotein that is involved in T-cell activation. The size difference between the two CD6 forms is due to differences in phosphorylation. CD6 mediates cellular adhesion and migration across the endothelial and epithelial cells. CD6 may bind in trans to surface glycoproteins. These transinteractions are reinforced during autoimmune diseases, like rheumatoid arthritis (RA), Sjögren′s syndrome, and multiple sclerosis and some cancers.

Immunogen

KLH-conjugated linear peptide corresponding to human CD6.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Antigen Affinity Purified

Quality

Evaluated by Immunohistochemistry in human spleen tissue.

Imunnohistochemistry Analysis: A 1:100 dilution of this antibody detected CD6 in human spleen tissue.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

140 kDa calculated