Analysis Note

ControlPC3 cell lysate

Application

Research Sub CategoryCytoskeleton

Detect CADM1 using this Anti-CADM1 Antibody validated for use in WB & IC.

Research CategoryCell Structure

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected CADM1 in NIH/3T3, A431, and HeLa cells.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

CADM1 (also known as cell adhesion molecule 1, Nectin-like protein 2, synaptic cell adhesion molecule. IgSF4 and TSLC-1) is a tumor suppressor part of the immunoglobulin superfamily and has been found to show reduced expression in many different solid tumors. CADM1 has also been found to play a role in the formation of epithelia-like cell structure. Recent research has also linked CADM1 to mediating emotional and social behaviors and motor skills. CADM1 may also be important in psychiatric and behavioral disorders such as autism.

Immunogen

Linear peptide corresponding to human CADM1.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blot in PC3 cell lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected CADM1 in 10 µg of PC3 cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~48 kDa & 37 kDa observed.
Isoform 1 (48 kDa), Isoform 2 (37 kDa).