Anti-BCMA

Application

Research CategoryApoptosis & Cancer

Research Sub CategoryApoptosis - Additional

Immunohistochemistry Analysis: 10 µg/mL from a representative lot detected BCMA in human spleen cells.

Immunofluorescence Analysis: 10 µg/mL from a representative lot detected BCMA in human spleen cells.

Anti-BCMA Antibody is a highly specific rabbit polyclonal antibody, that targets B-cell Maturation Protein & has been tested in western blotting, IHC & Immunofluorescence.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

BCMA (also known as Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein, and CD269) is a receptor of BAFF. BCMA, like TACI, binds BAFF and April. BAFF and its receptors induce B cell development and survival, activate NF-kB and c-Jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human BCMA.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Quality

Evaluated by Western Blotting in human spleen, K562, and U937 lysates.

Western Blotting Analysis: 5 µg/mL of this antibody detected BCMA in human spleen, K562, and U937 lysates.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~27 kDa observed. Uncharacterized bands may be observed in some lysate(s).