Biochem/physiol Actions

Baiap2 is an adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Baiap2 is necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Baiap2 is involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex.Baiap2 plays a role in neurite growth. Baiap2 acts syngeristically with ENAH to promote filipodia formation.

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Immunogen

Synthetic peptide directed towards the N terminal of human BAIAP2

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: LLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQG