Biochem/physiol Actions

On ligand binding, Amhr2 forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. It is a receptor for anti-Muellerian hormone.

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Immunogen

The immunogen for anti-AMHR2 antibody: synthetic peptide derected towards the N terminal of human AMHR2

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: PAAAQVSPNRRTCVFFEAPGVRGSTKTLGEMVDAGPGPPKGIRCLYSHCC