Application

Rabbit Anti-UNCX antibody is suitable for western blot applications at a concentration of 1µg/ml and for immunohistochemistry applications at 4-8µg/ml.

Biochem/physiol Actions

UNCX is a transcription factor involved in somitogenesis and neurogenesis. It is required for the maintenance and differentiation of particular elements of the axial skeleton. It may act upstream of PAX9. UNCX plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

UNCX is a homeobox transcription factor that regulates the survival and proliferation of neuronal cells in the olfactory epithelium. Studies in Xenopus laevis have revealed that UNCX is expressed in the pharyngeal pouch and sclerotome.Rabbit Anti-UNCX antibody recognizes human, and zebrafish UNCX.

Immunogen

Synthetic peptide directed towards the C terminal region of human UNCX

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: AAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPAEEPATCGVPEPG