Application

Rabbit Anti-TRIM31 antibody is suitable for western blot (0.5 µg/ml) and IHC (4-8 µg/ml) assays.

Biochem/physiol Actions

TRIM31 encodes for a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to both the cytoplasm and the nucleus.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

TRIM31 is a protein containing zinc-binding, B-box type, RING, and coiled-coil domains. Alterations in TRIM31 gene have been implicated in attention deficit/hyperactivity disorder (ADHD), whereas the changes in protein levels have been linked to gastric and non-small cell lung cancers. Rabbit Anti-TRIM31 antibody recognizes human, bovine, and mouse TRIM31.

Immunogen

Synthetic peptide directed towards the N terminal region of human TRIM31

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: CRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKAQGVHR