Biochem/physiol Actions

Tripartite motif containing 16 (TRIM16) is transcriptional repressor belonging to tripartite motif family. It is described as a tumor suppressor protein that interacts with vimentin and E2F1 proteins. It inhibits cell proliferation by inducing cell cycle arrest in G1/S phase in neuroblastoma cells. TRIM16 has the ability to heterodimerize with other TRIM proteins and exhibits E3 ubiquitin ligase activity.

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Immunogen

Synthetic peptide directed towards the N terminal region of human TRIM16

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: PLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDS