Anti-TFEB

Analysis Note

ControlA549 cell lysate

Application

Detect TFEB using this rabbit polyclonal antibody, Anti-TFEB Antibody validated for use in western blotting.

Research Sub CategoryNeurodegenerative Diseases

Research CategoryNeuroscience

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Transcription factor EB (TFEB) is a member of the MiT/TFE family of transcription factors that is translocated in a subset of renal tumors. It plays an important role in the signal transduction process required for normal vascularization of the placenta. TFEB specifically recognizes and binds the E-box sequence (5′-CANNTG-3′) and CLEAR box sequence (5′-GTCACGTGAC-3′).

Immunogen

KLH-conjugated linear peptide corresponding to human TFEB.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Quality

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TFEB in 15 µg of A549 cell lysate.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~57 kDa observed. Uniprot describes two isoforms at ~44 kDa and ~53 kDa Uncharacterized bands may appear in some lysates.