Application

Anti-SLC9A9 polyclonal antibody is used to tag solute carrier family 9 (sodium/hydrogen exchanger), member 9 for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of solute carrier family 9 (sodium/hydrogen exchanger), member 9 in the regulation of luminal pH of recycling endosomes and attention deficit hyperactivity disorder-like phenotype.

Biochem/physiol Actions

SLC9A9 may act in electroneutral exchange of protons for Na(+) across membranes.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Solute carrier family 9 (sodium/hydrogen exchanger), member 9 (SLC9A9, NHE9, Nbla00118) is a member of the sodium/hydrogen exchanger family is a membrane protein that regulates the luminal pH of the recycling endosome, an essential organelle for synaptic transmission and plasticity. Disruption of SLC9A9 may contribute to the attention deficit hyperactivity disorder-like phenotype.

Immunogen

Synthetic peptide directed towards the C terminal region of human SLC9A9

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: INYQEQASSPCSPPARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQT

Specificity

Anti-SLC9A9 polyclonal antibody reacts with chicken, bovine, human, and mouse solute carrier family 9 (sodium/hydrogen exchanger), member 9 proteins.