Application

Rabbit polyclonal anti-RAB3D antibody is used to tag RAB3D, member RAS oncogene family for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of RAB3D, member RAS oncogene family in exocytosis and transcytosis within non-neuronal secretory cells. Anti- RAB3D antibody produced in rabbit is suitable for western blotting at a concentration of 2.5 µg/ml.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

RAB3D, member RAS oncogene family (RAB3D, RAB16, RAD3D, GOV, D2-2) is a low molecular weight Ras-like GTPase involve in the regulation of intravesicle transport during exocytosis and apically directed transcytosis. RAB3D is found primarily in the secretory granules of non-neuronal exocrine secretory cells such as mast cells and pancreatic acinar cells.

Rabbit polyclonal anti-RAB3D antibody reacts with bovine, human, mouse, and rat RAB3D, member RAS oncogene family GTPases.

Immunogen

Synthetic peptide directed towards the C terminal region of human RAB3D

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: KENINVKQVFERLVDVICEKMNESLEPSSSSGSNGKGPAVGDAPAPQPSS