Application

Immunohistochemistry Analysis: A 1:100-500 dilution from a representative lot detected Prohibitin in human kidney and human ileum tissue.

Detect Prohibitin using this rabbit polyclonal antibody, Anti-Prohibitin Antibody validated for use in western blotting & IHC (Paraffin).

General description

Prohibitin is an inhibitor of DNA synthesis that is widely expressed across various tissues. Prohibitin influences proliferation, and may also have a role in regulating mitochondrial respiration activity and in aging. Expression levels of prohibitin in fibroblasts have been found to decrease heterogeneously as cellular aging occurs.

Immunogen

KLH-conjugated linear peptide corresponding to human Prohibitin near the N-Terminus.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Quality

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Prohibitin in 10 µg of human liver tissue lysate.

Specificity

Other homologies: Mouse (86% sequence homology).

This antibody recognizes Prohibitin near the N-Terminus.

Target description

~32 kDa observed