Biochem/physiol Actions

Pja2 has E2-dependent E3 ubiquitin-protein ligase activity. Pja2 is responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Pja2 is essential for PKA-mediated long-term memory processes.

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Immunogen

The immunogen for anti-PJA2 antibody: synthetic peptide derected towards the N terminal of human PJA2

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: PAGGYQTITGRRYGRRHAYVSFKPCMTRHERSLGRAGDDYEVLELDDVPK