Analysis Note

ControlRat Cerebellum Tissue

Application

Detect Galanin using this Anti-Galanin Antibody validated for use in IH(P).

Research CategoryNeuroscience

Research Sub CategoryNeurochemistry & Neurotrophins

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Galanin is a neuropeptide which is not a member of any known family of neuropeptides, despite repeated efforts to discover related peptides. Its actions are mediated via Gi-protein-coupled receptors (GPCR's) and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. Galanin and it's receptor are over expressed in limbic region of the brain in patients suffering from Alzheimer′s disease. However it is not clear whether galanin exacerbates or is a protective response to the disease.

Immunogen

Synthetic Linear Peptide

Physical form

Serum with 0.05% NaN3

Quality

Routinely evaluated by Immunhistochemistry on rat cerebellum tissue.

Specificity

Reactivity with other species has not been determined.

Cat. # AB2233 recognizes Galanin

Storage and Stability

Maintain at -20°C for up to 1 year from date of receipt.

Target description

13.3 kDa