Application

Anti-EGFL8 polyclonal antibody is used to tag EGF-like-domain, multiple 8 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of EGF-like-domain, multiple 8 protein as a potential prognostic marker for gastrointestinal cancers such as gastric cancer and colorectal cancer.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

EGF-like-domain, multiple 8 (EGFL8), an EGFL7 paralog, is downregulated in metastatic colorectal cancers (CRC) making it a potential prognostic marker for poor prognosis in CRC and advanced gastric cancer.

Immunogen

Synthetic peptide directed towards the C terminal region of human EGFL8

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: QAGAWVRAVLPVPPEELQPEQVAELWGRGDRIESLSDQVLLLEERLGACS

Specificity

Anti-EGFL8 polyclonal antibody reacts with pig, bovine, human, mouse, and rat EGF-like-domain, multiple 8 proteins.