Application
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry. The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies® protocols and other useful information.
Biochem/physiol Actions
Coiled-coil domain-containing protein 104 (CCDC104), commonly known as CFAP36 (cilia and flagella associated protein 36), functions as a binding partner of the ciliary protein Arl3 (ADP-ribosylation factor-like 3).
Features and Benefits
Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.Every Prestige Antibody is tested in the following ways: IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues. Protein array of 364 human recombinant protein fragments.
General description
Coiled-coil domain-containing protein 104 (CCDC104) is a widely expressed uncharacterized protein, which is localized predominantly to nucleus, and is also found in cytoplasm. It is composed of a coiled-coil region in its C-terminal, followed by two α-helices and a BART (binder of Arl2) domain in the N-terminal.
Immunogen
cilia and flagella associated protein 36
Legal Information
Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC
Linkage
Corresponding Antigen APREST71512.
Physical form
Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide
This product has met the following criteria: