Application

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected ARMS2 in human placenta tissue.

This Anti-ARMS2 Antibody is validated for use in Immunohistochemistry (Paraffin) for the detection of ARMS2.

Research CategoryNeuroscience

Research Sub CategoryDevelopmental Signaling

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Age-related maculopathy susceptibility protein 2 (ARMS2) is highly expressed in the human placenta and retina. The biological function of ARMS2 has not been fully characterized. However, previous studies have linked mutations in the ARMS2 and HtrA1 genes, located on chromosome 10q26, to the occurrence of age-related macular degeneration type 8, a condition of irreversible vision loss in the elderly.

Immunogen

GST-tagged recombinant protein corresponding to human ARMS2.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Immunohistochemistry in human retina tissue.

Immunohistochemistry Analysis: A 1:2,000 dilution of this antibody detected ARMS2 in human retina tissue.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

15 kDa calculated