Biochem/physiol Actions

Primary TargetM₂

General description

Selective presynaptic muscarinic receptor M₂ antagonist with cardioselectivity. Exhibits antiarrhythmic effects in vivo, also shown to reverse the memory impairment effect of insulin in a mouse model.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Lanzafame A., et al. 2001. Eur J Pharmacol.416, 235.r>Kopf S., et al. 1998. Neurobiol Learn Mem.70, 305.Naito, H., et al. 1997. Heart Vessels.12, 229.Hammer, R., et al. 1986. Life Sci.38, 1653.

Packaging

10 mg in Glass bottle

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Harmful (C)