ADAPHOSTIN

Code: SML1110-5MG D2-231

Biochem/physiol Actions

Adaphostin is a p210bcr/abl tyrosine kinase inhibitor displaying anti-proliferative activity in leukemia models, human prostate cancer cell line PC-3 ...


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Your Price
€93.50 5MG
€115.01 inc. VAT

Biochem/physiol Actions

Adaphostin is a p210bcr/abl tyrosine kinase inhibitor displaying anti-proliferative activity in leukemia models, human prostate cancer cell line PC-3 and other cancer cell lines. Adaphostin is a potent inducer of myeloid cell death. Similarly to AG957, adaphostin appears to induce a degradation of WT and mutated Bcr/Abl.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyYJZSUCFGHXQWDM-ONHXBKDTSA-N
InChI1S/C24H27NO4/c26-21-5-6-22(27)19(10-21)14-25-20-3-1-18(2-4-20)23(28)29-24-11-15-7-16(12-24)9-17(8-15)13-24/h1-6,10,15-17,25-27H,7-9,11-14H2/t15-,16+,17-,24-
Quality Level100
SMILES stringO=C(C1=CC=C(NCC2=CC(O)=CC=C2O)C=C1)OC34C[C@@]5([H])C[C@@](C[C@@](C5)([H])C4)([H])C3
solubilityDMSO: 20 mg/mL, clear
storage conditiondesiccated
storage temp.2-8°C
Cas Number241127-58-2
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