A-278637

Code: SML1033-25MG D2-231

Biochem/physiol Actions

A-278637 is a selective opener of ATP-sensitive K (KATP) channels (EC50 = 102 nM) that blocks contraction of bladder smooth muscle in both ...


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€339.60 25MG
€417.71 inc. VAT
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Biochem/physiol Actions

A-278637 is a selective opener of ATP-sensitive K (KATP) channels (EC50 = 102 nM) that blocks contraction of bladder smooth muscle in both in vivo and in vitro assays. A-278637 is 15-fold more selective than nifedipine for bladder compared other smooth muscle KATP channels, and displays reduced effects on mean arterial pressure compared to other channel openers.

Packaging

5, 25 mg in glass bottle

assay≥98%
colorwhite to beige
formpowder
optical activity[α]/D -44 to -54°, c = 0.1 in acetonitrile
Quality Level100
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
Cas Number227609-66-7
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