Biochem/physiol Actions

Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1β, however not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection.

General description

Monophosphoryl lipid A (MPLA) is an analog of the lipid A moiety. It is regarded as a detoxified derivative of the lipopolysaccharide (LPS).

Other Notes

For R&D use only. Not for drug, household, or other uses.

Packaging

2 mL Amber Glass Crimp Cap Vial (699851P-5mg)

2 mL Amber Glass Crimp Cap Vial (699851P-1mg)