Biochem/physiol Actions
15(S)-HETE plays a role in various biological actions. It may play a role in pathogenesis and prevention of airway inflammatory disorders. 15(S)-HETE is involved in inhibiting cell proliferation and induces apoptosis in various human cancers.
General description
15(S)-HETE is a product of the arachidonic acid pathway. It is synthesized by the human lungs and airway epithelial cells. 15(S)-HETE is a potent mucosecretagogue in human airways. It is a metabolite of 15-lipoxygenase. 15(S)-HETE is an endogenous ligand for peroxisome proliferator-activated receptor γ (PPARγ).
Packaging
2 mL Amber Glass Sealed Ampule (900128E-100UG and 900128E-500UG)
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