Application

Takasago Ligands and Complexes for Asymmetric Reactions

Catalytic ligand used for:•Nickel-catalyzed asymmetric A-arylation and heteroarylation of ketones with chloroarenes•Enantioselective synthesis of dihydrobenzofurans and dihydronaphthofurans via olefin isomerization/enantioselective intramolecular Alder-ene reaction of enynes catalyzed by Rh•Preparation of axially chiral biaryl compounds by gold-catalyzed stereoselective intramolecular hydroarylation•Preparation of chiral silylated homoallylic alcohols and diols by asymmetric addition of alcohols and aldehydes to silylbutadienes catalyzed by ruthenium complexes•Preparation of chiral 3-alkyl-substituted indolines by tandem condensation-asymmetric hydrogenation of indoles with aldehydes, catalyzed by Bronsted acids and palladium BINAP complexes•Rhodium-catalyzed asymmetric formal olefination or cycloaddition of 1,3-dicarbonyl compounds with 1,6-diynes or 1,6-enynes

Legal Information

Sold in collaboration with Takasago for research purposes only. JP Registration No. 3148136

SEGPHOS is a registered trademark of Takasago Intl. Corp.

Packaging

100 mg in amber glass bottle

50 mg in glass bottle