Anti-MARCH1

Code: SAB2101432-100UL D2-231

Biochem/physiol Actions

MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting t...


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€577.00 100UL
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Biochem/physiol Actions

MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide directed towards the N terminal region of human MARCH1

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Sequence

Synthetic peptide located within the following region: LQASSPTTGTAPRSQSRLSVCPSTQDICRICHCEGDEESPLITPCRCTGT

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
concentration0.5 mg - 1 mg/mL
conjugateunconjugated
formbuffered aqueous solution
Gene Informationhuman ... MARCH1(55016)
mol wt31 kDa
Quality Level100
shipped inwet ice
species reactivityrat, dog, human, mouse, rabbit, bovine, horse, guinea pig
storage temp.−20°C
technique(s)western blot: suitable
UniProt accession no.Q8TCQ1-2
This product has met the following criteria: