Anti-Mouse IgM; Human ads;Gt;AP 1ML

Application

Goat anti-Mouse IgM µ chain Antibody, Alkaline Phosphatase conjugate, Species Adsorbed detects level of Mouse IgM µ chain & has been published & validated for use in ELISA.

General description

IgM constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as ′natural′ blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Purified by affinity chromatography on mouse IgM covalently linked to agarose. Liquid in 50mM Tris/1mM MgCl₂/50% Glycerol, pH 8.0, containing 0.1% NaN₃ as preservative.

Specificity

Reacts with heavy chain of mouse IgM. Absorbed for mouse IgG1, IgG2a, IgG2b, IgG3 and IgA, pooled human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins. Reactivity with other species has not been determined.